When an organization grows so large that people working for it loose contact with the intended result of the organization is begins to die.
This situation leads to the belief that the organization itself is of importance, even though it was just created to solve a specific issue. And the people working in the organization loose focus of the organizations function and the organization starts growing in areas without return, administration and administration of administration.
The way to make sure this does not happen is to keep organizations small. Create another organization to solve a new problem, do not grow the old one.